The purpose of this study was to investigate the effect of mindfulness techniques on depression and anxiety in patients with certain phobia disorder. The present study was a semi-experimental study with pre-test and post-test design with control group. The statistical population of this study was all individuals with specific phobia disorder in Shiraz in 1397. The sample consisted of 30 subjects selected through available sampling method and randomly divided into two experimental groups (15 subjects) and control group 15 people). The questionnaires that were used to collect information from the sample group included the psychological syllabus checklist SCL.90.R. At first, the subjects of both groups were pre-test and then the experimental group received 6 sessions of two-hour sessions of mindfulness techniques. After the end of intervention on the experimental group, subjects of both groups were evaluated by post-test. For statistical analysis of data, covariance analysis was performed using SPSS software. The results showed that there was a significant difference between the mean scores of depression and anxiety in the experimental and control groups in the post-test (P <0.01). Therefore, teaching mind-consciousness techniques is an effective method for depression and anxiety in individuals with a specific phobia disorder.